Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A

Secretory immunoglobulin A (sIgA), a dimeric antibody found in high quantities in the gastrointestinal mucosa, is broadly associated with mucosal immune protection. A distinguishing feature of sIgA is its ability to crosslink pathogens, thereby creating pathogen/sIgA aggregates that are too large to...

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Detalles Bibliográficos
Autores principales: Chen, Alex, McKinley, Scott A., Shi, Feng, Wang, Simi, Mucha, Peter J., Harit, Dimple, Forest, M. Gregory, Lai, Samuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488843/
https://www.ncbi.nlm.nih.gov/pubmed/26132216
http://dx.doi.org/10.1371/journal.pone.0131351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488843/
https://www.ncbi.nlm.nih.gov/pubmed/26132216
http://dx.doi.org/10.1371/journal.pone.0131351

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