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Resistance of R-Ras knockout mice to skin tumour induction

The R-ras gene encodes a small GTPase that is a member of the Ras family. Despite close sequence similarities, R-Ras is functionally distinct from the prototypic Ras proteins; no transformative activity and no activating mutations of R-Ras in human malignancies have been reported for it. R-Ras activ...

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Detalles Bibliográficos
Autores principales: May, Ulrike, Prince, Stuart, Vähätupa, Maria, Laitinen, Anni M., Nieminen, Katriina, Uusitalo-Järvinen, Hannele, Järvinen, Tero A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488886/
https://www.ncbi.nlm.nih.gov/pubmed/26133397
http://dx.doi.org/10.1038/srep11663