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Incidence of cardiovascular events and gastrointestinal bleeding in patients receiving clopidogrel with and without proton pump inhibitors: an updated meta-analysis

BACKGROUND: Dual antiplatelet therapy is the standard of care after coronary stent placement but increases the bleeding risk. The effects of proton pump inhibitors (PPIs) on clopidogrel metabolism have been described, but the clinical significance is not yet definitive. We aimed to do an updated met...

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Detalles Bibliográficos
Autores principales: Cardoso, Rhanderson N, Benjo, Alexandre M, DiNicolantonio, James J, Garcia, Daniel C, Macedo, Francisco Y B, El-Hayek, Georges, Nadkarni, Girish N, Gili, Sebastiano, Iannaccone, Mario, Konstantinidis, Ioannis, Reilly, John P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488889/
https://www.ncbi.nlm.nih.gov/pubmed/26196021
http://dx.doi.org/10.1136/openhrt-2015-000248