Effects of Integrating and Non-Integrating Reprogramming Methods on Copy Number Variation and Genomic Stability of Human Induced Pluripotent Stem Cells

Human-induced pluripotent stem cells (iPSCs) are derived from differentiated somatic cells using defined factors and provide a renewable source of autologous cells for cell therapy. Many reprogramming methods have been employed to generate human iPSCs, including the use of integrating vectors and no...

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Detalles Bibliográficos
Autores principales: Kang, Xiangjin, Yu, Qian, Huang, Yuling, Song, Bing, Chen, Yaoyong, Gao, Xingcheng, He, Wenyin, Sun, Xiaofang, Fan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488894/
https://www.ncbi.nlm.nih.gov/pubmed/26131765
http://dx.doi.org/10.1371/journal.pone.0131128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488894/
https://www.ncbi.nlm.nih.gov/pubmed/26131765
http://dx.doi.org/10.1371/journal.pone.0131128

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