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Identification of novel monocistronic HTLV-1 mRNAs encoding functional Rex isoforms

BACKGROUND: Human T cell leukemia virus type 1 (HTLV-1) gene expression is controlled by the key regulatory proteins Tax and Rex. The concerted action of these proteins results in a two-phase kinetics of viral expression that depends on a time delay between their action. However, it is difficult to...

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Detalles Bibliográficos
Autores principales: Rende, Francesca, Cavallari, Ilaria, Andresen, Vibeke, Valeri, Valerio W, D’Agostino, Donna M, Franchini, Genoveffa, Ciminale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488940/
https://www.ncbi.nlm.nih.gov/pubmed/26133546
http://dx.doi.org/10.1186/s12977-015-0184-2