TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill

BACKGROUND: TRAIL is a potent and specific inducer of apoptosis in tumour cells and therefore is a possible new cancer treatment. It triggers apoptosis by binding to its cognate, death-inducing receptors, TRAIL-R1 and TRAIL-R2. In order to increase its activity, receptor-specific ligands and agonist...

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Detalles Bibliográficos
Autores principales: Mohr, Andrea, Yu, Rui, Zwacka, Ralf M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489125/
https://www.ncbi.nlm.nih.gov/pubmed/26138346
http://dx.doi.org/10.1186/s12885-015-1508-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489125/
https://www.ncbi.nlm.nih.gov/pubmed/26138346
http://dx.doi.org/10.1186/s12885-015-1508-2

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