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GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors

BACKGROUND: Protein sequence alignments and database search methods use standard scoring matrices calculated from amino acid substitution frequencies in general sets of proteins. These general-purpose matrices are not optimal to align accurately sequences with marked compositional biases, such as hy...

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Detalles Bibliográficos
Autores principales: Rios, Santiago, Fernandez, Marta F., Caltabiano, Gianluigi, Campillo, Mercedes, Pardo, Leonardo, Gonzalez, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489126/
https://www.ncbi.nlm.nih.gov/pubmed/26134144
http://dx.doi.org/10.1186/s12859-015-0639-4