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GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors
BACKGROUND: Protein sequence alignments and database search methods use standard scoring matrices calculated from amino acid substitution frequencies in general sets of proteins. These general-purpose matrices are not optimal to align accurately sequences with marked compositional biases, such as hy...
Autores principales: | Rios, Santiago, Fernandez, Marta F., Caltabiano, Gianluigi, Campillo, Mercedes, Pardo, Leonardo, Gonzalez, Angel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489126/ https://www.ncbi.nlm.nih.gov/pubmed/26134144 http://dx.doi.org/10.1186/s12859-015-0639-4 |
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