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Preoperative serum 8-hydroxydeoxyguanosine is associated with chemoresistance and is a powerful prognostic factor in endometrioid-type epithelial ovarian cancer

BACKGROUND: Oxidative stress is a widely seen phenomenon in several carcinomas. Increasing evidence also suggests that it has a significant role in the development of epithelial ovarian carcinoma (EOC). 8-Hydroxydeoxyguanosine (8-OHdG) is one of the main indicators of oxidative stress and increased...

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Detalles Bibliográficos
Autores principales: Pylväs-Eerola, Marjo, Karihtala, Peeter, Puistola, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489129/
https://www.ncbi.nlm.nih.gov/pubmed/26134400
http://dx.doi.org/10.1186/s12885-015-1504-6