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Unmet clinical needs in chronic migraine: Rationale for study and design of COMPEL, an open-label, multicenter study of the long-term efficacy, safety, and tolerability of onabotulinumtoxinA for headache prophylaxis in adults with chronic migraine

BACKGROUND: Chronic migraine is a neurological condition with a large individual and socioeconomic burden of disease. The recently completed Phase III REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) clinical development program established the efficacy and safety of onabotulinumtoxinA as...

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Detalles Bibliográficos
Autores principales: Blumenfeld, Andrew M., Aurora, Sheena K., Laranjo, Karen, Papapetropoulos, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489131/
https://www.ncbi.nlm.nih.gov/pubmed/26133547
http://dx.doi.org/10.1186/s12883-015-0353-x