FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice

BACKGROUND: Haploinsufficiency of the FOXL2 transcription factor in humans causes Blepharophimosis/Ptosis/Epicanthus Inversus syndrome (BPES), characterized by eyelid anomalies and premature ovarian failure. Mice lacking Foxl2 recapitulate human eyelid/forehead defects and undergo female gonadal dys...

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Detalles Bibliográficos
Autores principales: Marongiu, Mara, Marcia, Loredana, Pelosi, Emanuele, Lovicu, Mario, Deiana, Manila, Zhang, Yonqing, Puddu, Alessandro, Loi, Angela, Uda, Manuela, Forabosco, Antonino, Schlessinger, David, Crisponi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489133/
https://www.ncbi.nlm.nih.gov/pubmed/26134413
http://dx.doi.org/10.1186/s12861-015-0072-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489133/
https://www.ncbi.nlm.nih.gov/pubmed/26134413
http://dx.doi.org/10.1186/s12861-015-0072-y

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