Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD

BACKGROUND: Only a handful of signaling pathways are major actors of development and responsible for both the conservation and the diversification of animal morphologies. To explain this twofold nature, gene duplication and enhancer evolution were predominantly put forth as tinkering mechanisms wher...

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Detalles Bibliográficos
Autores principales: Sadier, Alexa, Lambert, Elise, Chevret, Pascale, Décimo, Didier, Sémon, Marie, Tohmé, Marie, Ruggiero, Florence, Ohlmann, Théophile, Pantalacci, Sophie, Laudet, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489351/
https://www.ncbi.nlm.nih.gov/pubmed/26134525
http://dx.doi.org/10.1186/s12862-015-0395-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489351/
https://www.ncbi.nlm.nih.gov/pubmed/26134525
http://dx.doi.org/10.1186/s12862-015-0395-0

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