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Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD
BACKGROUND: Only a handful of signaling pathways are major actors of development and responsible for both the conservation and the diversification of animal morphologies. To explain this twofold nature, gene duplication and enhancer evolution were predominantly put forth as tinkering mechanisms wher...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489351/ https://www.ncbi.nlm.nih.gov/pubmed/26134525 http://dx.doi.org/10.1186/s12862-015-0395-0 |