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A Semiquantitative Framework for Gene Regulatory Networks: Increasing the Time and Quantitative Resolution of Boolean Networks

Boolean models have been instrumental in predicting general features of gene networks and more recently also as explorative tools in specific biological applications. In this study we introduce a basic quantitative and a limited time resolution to a discrete (Boolean) framework. Quantitative resolut...

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Detalles Bibliográficos
Autores principales: Kerkhofs, Johan, Geris, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489432/
https://www.ncbi.nlm.nih.gov/pubmed/26067297
http://dx.doi.org/10.1371/journal.pone.0130033