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Structure-based drug design studies of the interactions of ent-kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca(2+)-ATPase PfATP6

Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current chemotherapeutic antimalarial arsenal, the search for new antimalarial drugs remains urgent though hampered by a lack of knowledge regarding the...

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Detalles Bibliográficos
Autores principales: Guimarães, Daniel Silqueira Martins, da Fonseca, Amanda Luisa, Batista, Ronan, Comar, Moacyr, de Oliveira, Alaíde Braga, Taranto, Alex Gutterres, Varotti, Fernando de Pilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489458/
https://www.ncbi.nlm.nih.gov/pubmed/25946251
http://dx.doi.org/10.1590/0074-02760140415