A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole

Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly attributed to variable drug susceptibility among Trypanosoma cruzi strains. ATP-binding cassette (ABC) transporters are involved in a variety of...

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Detalles Bibliográficos
Autores principales: Zingales, Bianca, Araujo, Rafael Gomes Aquino, Moreno, Margoth, Franco, Jaques, Aguiar, Pedro Henrique Nascimento, Nunes, Solange Lessa, Silva, Marcelo Nunes, Ienne, Susan, Machado, Carlos Renato, Brandão, Adeilton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489481/
https://www.ncbi.nlm.nih.gov/pubmed/25946152
http://dx.doi.org/10.1590/0074-02760140407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489481/
https://www.ncbi.nlm.nih.gov/pubmed/25946152
http://dx.doi.org/10.1590/0074-02760140407

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