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Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-κB-Nuclear Translocation

BACKGROUND: Hepatitis C virus (HCV) infection is one of the major causes of cirrhosis and hepatocellular carcinoma. HCV nonstructural protein 5A (NS5A) is an attractive antiviral target and plays an important role in HCV replication as well as hepatocarcinogenesis. The aim of this study was to asses...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Kanda, Tatsuo, Wu, Shuang, Nakamoto, Shingo, Nakamura, Masato, Sasaki, Reina, Haga, Yuki, Wakita, Takaji, Shirasawa, Hiroshi, Yokosuka, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489642/
https://www.ncbi.nlm.nih.gov/pubmed/26133378
http://dx.doi.org/10.1371/journal.pone.0131973