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Treatment of Prion Disease with Heterologous Prion Proteins

Prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy in cattle, and scrapie in sheep are fatal neurodegenerative diseases for which there is no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cel...

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Detalles Bibliográficos
Autores principales: Skinner, Pamela J., Kim, Hyeon O., Bryant, Damani, Kinzel, Nikilyn J., Reilly, Cavan, Priola, Suzette A., Ward, Anne E., Goodman, Patricia A., Olson, Katherine, Seelig, Davis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489745/
https://www.ncbi.nlm.nih.gov/pubmed/26134409
http://dx.doi.org/10.1371/journal.pone.0131993