Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments

Nucleotide alterations detected by next generation sequencing are not always true biological changes but could represent sequencing errors. Even highly accurate methods can yield substantial error rates when applied to millions of nucleotides. In this study, we examined the reproducibility of nucleo...

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Detalles Bibliográficos
Autores principales: Qi, Yuan, Liu, Xiuping, Liu, Chang-gong, Wang, Bailing, Hess, Kenneth R., Symmans, W. Fraser, Shi, Weiwei, Pusztai, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489803/
https://www.ncbi.nlm.nih.gov/pubmed/26136146
http://dx.doi.org/10.1371/journal.pone.0119230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489803/
https://www.ncbi.nlm.nih.gov/pubmed/26136146
http://dx.doi.org/10.1371/journal.pone.0119230

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