Cargando…
Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments
Nucleotide alterations detected by next generation sequencing are not always true biological changes but could represent sequencing errors. Even highly accurate methods can yield substantial error rates when applied to millions of nucleotides. In this study, we examined the reproducibility of nucleo...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489803/ https://www.ncbi.nlm.nih.gov/pubmed/26136146 http://dx.doi.org/10.1371/journal.pone.0119230 |