Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells

Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries and identified mefloquine, an anti-malaria medicine, as a potent...

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Detalles Bibliográficos
Autores principales: Shin, Ji Hyun, Bae, Dong-Jun, Kim, Eun Sung, Kim, Han Byeol, Park, So Jung, Jo, Yoon Kyung, Jo, Doo Sin, Jo, Dong-Gyu, Kim, Sang-Yeob, Cho, Dong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489826/
https://www.ncbi.nlm.nih.gov/pubmed/26157548
http://dx.doi.org/10.4062/biomolther.2015.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489826/
https://www.ncbi.nlm.nih.gov/pubmed/26157548
http://dx.doi.org/10.4062/biomolther.2015.025

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