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Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells
Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries and identified mefloquine, an anti-malaria medicine, as a potent...
Autores principales: | Shin, Ji Hyun, Bae, Dong-Jun, Kim, Eun Sung, Kim, Han Byeol, Park, So Jung, Jo, Yoon Kyung, Jo, Doo Sin, Jo, Dong-Gyu, Kim, Sang-Yeob, Cho, Dong-Hyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489826/ https://www.ncbi.nlm.nih.gov/pubmed/26157548 http://dx.doi.org/10.4062/biomolther.2015.025 |
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