Cargando…

Evaluation of Eye Irritation Potential of Solid Substance with New 3D Reconstructed Human Cornea Model, MCTT HCE(TM)

The eye irritation potential of drug candidates or pharmaceutical ingredients should be evaluated if there is a possibility of ocular exposure. Traditionally, the ocular irritation has been evaluated by the rabbit Draize test. However, rabbit eyes are more sensitive to irritants than human eyes, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Won-hee, Jung, Kyoung-mi, Yang, Hye-ri, Lee, Miri, Jung, Haeng-Sun, Lee, Su-Hyon, Park, Miyoung, Lim, Kyung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489834/
https://www.ncbi.nlm.nih.gov/pubmed/26157556
http://dx.doi.org/10.4062/biomolther.2015.004