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Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

BACKGROUND: Numerous risk prediction algorithms based on conventional risk factors for Coronary Heart Disease (CHD) are available but provide only modest discrimination. The inclusion of genetic information may improve clinical utility. METHODS: We tested the use of two gene scores (GS) in the prosp...

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Detalles Bibliográficos
Autores principales: Beaney, Katherine E., Cooper, Jackie A., Ullah Shahid, Saleem, Ahmed, Waqas, Qamar, Raheel, Drenos, Fotios, Crockard, Martin A., Humphries, Steve E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489836/
https://www.ncbi.nlm.nih.gov/pubmed/26133560
http://dx.doi.org/10.1371/journal.pone.0130754