Cargando…

Uncovering Molecular Bases Underlying Bone Morphogenetic Protein Receptor Inhibitor Selectivity

Abnormal alteration of bone morphogenetic protein (BMP) signaling is implicated in many types of diseases including cancer and heterotopic ossifications. Hence, small molecules targeting BMP type I receptors (BMPRI) to interrupt BMP signaling are believed to be an effective approach to treat these d...

Descripción completa

Detalles Bibliográficos
Autores principales: Alsamarah, Abdelaziz, LaCuran, Alecander E., Oelschlaeger, Peter, Hao, Jijun, Luo, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489870/
https://www.ncbi.nlm.nih.gov/pubmed/26133550
http://dx.doi.org/10.1371/journal.pone.0132221