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Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion
The prion hypothesis postulates that the infectious agent in transmissible spongiform encephalopathies (TSEs) is an unorthodox protein conformation based agent. Recent successes in generating mammalian prions in vitro with bacterially expressed recombinant prion protein provide strong support for th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489884/ https://www.ncbi.nlm.nih.gov/pubmed/26136122 http://dx.doi.org/10.1371/journal.ppat.1004958 |