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Simultaneous Determination of Underivatized Vitamin B1 and B6 in Whole Blood by Reversed Phase Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry

BACKGROUND: Vitamin B1 (thiamine-diphosphate) and B6 (pyridoxal-5’phosphate) are micronutrients. Analysis of these micronutrients is important to diagnose potential deficiency which often occurs in elderly people due to malnutrition, in severe alcoholism and in gastrointestinal compromise due to byp...

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Detalles Bibliográficos
Autores principales: Puts, Johan, de Groot, Monique, Haex, Martin, Jakobs, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489891/
https://www.ncbi.nlm.nih.gov/pubmed/26134844
http://dx.doi.org/10.1371/journal.pone.0132018