Cargando…

Neuroimaging Analysis of the Dopamine Basis for Apathetic Behaviors in an MPTP-Lesioned Primate Model

Apathy commonly occurs in Parkinson disease (PD) patients; however, the role of dopamine in the pathophysiology of apathy remains elusive. We previously demonstrated that dopaminergic dysfunction within the ventral tegmental area (VTA)-nucleus accumbens (NAcc) pathway contributes to the manifestatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, LinLin, Xia, Yuanxuan, Flores, Hubert P., Campbell, Meghan C., Moerlein, Stephen M., Perlmutter, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489892/
https://www.ncbi.nlm.nih.gov/pubmed/26135399
http://dx.doi.org/10.1371/journal.pone.0132064