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Neuroimaging Analysis of the Dopamine Basis for Apathetic Behaviors in an MPTP-Lesioned Primate Model
Apathy commonly occurs in Parkinson disease (PD) patients; however, the role of dopamine in the pathophysiology of apathy remains elusive. We previously demonstrated that dopaminergic dysfunction within the ventral tegmental area (VTA)-nucleus accumbens (NAcc) pathway contributes to the manifestatio...
Autores principales: | Tian, LinLin, Xia, Yuanxuan, Flores, Hubert P., Campbell, Meghan C., Moerlein, Stephen M., Perlmutter, Joel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489892/ https://www.ncbi.nlm.nih.gov/pubmed/26135399 http://dx.doi.org/10.1371/journal.pone.0132064 |
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