IL-1 Receptor Antagonist Treatment Aggravates Staphylococcal Septic Arthritis and Sepsis in Mice

BACKGROUND: Interleukin-1 receptor antagonist (IL-1Ra) is the primary therapy against autoinflammatory syndromes with robust efficacy in reducing systemic inflammation and associated organ injury. However, patients receiving IL-1Ra might be at increased risk of acquiring serious infections. AIMS: To...

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Detalles Bibliográficos
Autores principales: Ali, Abukar, Na, Manli, Svensson, Mattias N. D., Magnusson, Malin, Welin, Amanda, Schwarze, Jan-Christoph, Mohammad, Majd, Josefsson, Elisabet, Pullerits, Rille, Jin, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489902/
https://www.ncbi.nlm.nih.gov/pubmed/26135738
http://dx.doi.org/10.1371/journal.pone.0131645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489902/
https://www.ncbi.nlm.nih.gov/pubmed/26135738
http://dx.doi.org/10.1371/journal.pone.0131645

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