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Cohesin-mediated interactions organize chromosomal domain architecture

To ensure proper gene regulation within constrained nuclear space, chromosomes facilitate access to transcribed regions, while compactly packaging all other information. Recent studies revealed that chromosomes are organized into megabase-scale domains that demarcate active and inactive genetic elem...

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Detalles Bibliográficos
Autores principales: Sofueva, Sevil, Yaffe, Eitan, Chan, Wen-Ching, Georgopoulou, Dimitra, Vietri Rudan, Matteo, Mira-Bontenbal, Hegias, Pollard, Steven M, Schroth, Gary P, Tanay, Amos, Hadjur, Suzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489921/
https://www.ncbi.nlm.nih.gov/pubmed/24185899
http://dx.doi.org/10.1038/emboj.2013.237