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Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study

BACKGROUND: Receptors in tumor blood vessels are attractive targets for ligand-directed drug discovery and development. The authors have worked systematically to map human endothelial receptors (“vascular zip codes”) within tumors through direct peptide library selection in cancer patients. Previous...

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Detalles Bibliográficos
Autores principales: Pasqualini, Renata, Millikan, Randall E, Christianson, Dawn R, Cardó-Vila, Marina, Driessen, Wouter H P, Giordano, Ricardo J, Hajitou, Amin, Hoang, Anh G, Wen, Sijin, Barnhart, Kirstin F, Baze, Wallace B, Marcott, Valerie D, Hawke, David H, Do, Kim-Anh, Navone, Nora M, Efstathiou, Eleni, Troncoso, Patricia, Lobb, Roy R, Logothetis, Christopher J, Arap, Wadih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490036/
https://www.ncbi.nlm.nih.gov/pubmed/25832466
http://dx.doi.org/10.1002/cncr.29344