Molecular mechanism of vinculin activation and nano-scale spatial organization in focal adhesions

Focal adhesions (FAs) link the extracellular matrix (ECM) to the actin cytoskeleton to mediate cell adhesion, migration, mechanosensing and signaling. FAs have conserved nanoscale protein organization, suggesting that the position of proteins within FAs regulates their activity and function. Vinculi...

Descripción completa

Detalles Bibliográficos
Autores principales: Case, Lindsay B., Baird, Michelle A., Shtengel, Gleb, Campbell, Sharon L., Hess, Harald F., Davidson, Michael W., Waterman, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490039/
https://www.ncbi.nlm.nih.gov/pubmed/26053221
http://dx.doi.org/10.1038/ncb3180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490039/
https://www.ncbi.nlm.nih.gov/pubmed/26053221
http://dx.doi.org/10.1038/ncb3180

Ejemplares similares