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Telomerase deficiency delays renal recovery in mice after ischemia reperfusion injury by impairing autophagy

The aged population suffers increased morbidity and higher mortality in response to episodes of acute kidney injury (AKI). Aging is associated with telomere shortening, and both telomerase reverse transcriptase (TerT) and RNA (TerC) are essential to maintain telomere length. To define a role of telo...

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Detalles Bibliográficos
Autores principales: Cheng, Huifang, Fan, Xiaofeng, Lawson, William E., Paueksakon, Paisit, Harris, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490111/
https://www.ncbi.nlm.nih.gov/pubmed/25760322
http://dx.doi.org/10.1038/ki.2015.69