Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune responses to facilitate tumour clearance. Reovirus is safe, well tolerated and currently in clinical testing for the treatment of multiple myelo...

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Detalles Bibliográficos
Autores principales: Parrish, C, Scott, G B, Migneco, G, Scott, K J, Steele, L P, Ilett, E, West, E J, Hall, K, Selby, P J, Buchanan, D, Varghese, A, Cragg, M S, Coffey, M, Hillmen, P, Melcher, A A, Errington-Mais, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://www.ncbi.nlm.nih.gov/pubmed/25814029
http://dx.doi.org/10.1038/leu.2015.88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490165/
https://www.ncbi.nlm.nih.gov/pubmed/25814029
http://dx.doi.org/10.1038/leu.2015.88

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