Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT(3A) receptors due to the action of flavonoids

The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT(3) receptor antagonism, due to the involvement of these receptors in such pathophysiological processes. E.g., setrons, s...

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Detalles Bibliográficos
Autores principales: Herbrechter, Robin, Ziemba, Paul M., Hoffmann, Katrin M., Hatt, Hanns, Werner, Markus, Gisselmann, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490227/
https://www.ncbi.nlm.nih.gov/pubmed/26191003
http://dx.doi.org/10.3389/fphar.2015.00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490227/
https://www.ncbi.nlm.nih.gov/pubmed/26191003
http://dx.doi.org/10.3389/fphar.2015.00130

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