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Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5-HT(3A) receptors due to the action of flavonoids
The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT(3) receptor antagonism, due to the involvement of these receptors in such pathophysiological processes. E.g., setrons, s...
Autores principales: | Herbrechter, Robin, Ziemba, Paul M., Hoffmann, Katrin M., Hatt, Hanns, Werner, Markus, Gisselmann, Günter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490227/ https://www.ncbi.nlm.nih.gov/pubmed/26191003 http://dx.doi.org/10.3389/fphar.2015.00130 |
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