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A functional polymorphism in the prodynorphin gene affects cognitive flexibility and brain activation during reversal learning

Whether the opioid system plays a role in the ability to flexibly adapt behavior is still unclear. We used fMRI to investigate the effect of a nucleotide tandem repeat (68-bp VNTR) functional polymorphism of the prodynorphin (PDYN) gene on cerebral activation during a reversal learning task in which...

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Detalles Bibliográficos
Autores principales: Votinov, Mikhail, Pripfl, Juergen, Windischberger, Christian, Moser, Ewald, Sailer, Uta, Lamm, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490246/
https://www.ncbi.nlm.nih.gov/pubmed/26190983
http://dx.doi.org/10.3389/fnbeh.2015.00172