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In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome

Defects in the rat sarcoma viral oncogene homolog (Ras)/extracellular-signal-regulated kinase and the phosphatidylinositol 3-kinase-mammalian target of rapamycin (mTOR) signaling pathways are responsible for several neurodevelopmental disorders. These disorders are an important cause for intellectua...

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Detalles Bibliográficos
Autores principales: Wang, Tiantian, de Kok, Laura, Willemsen, Rob, Elgersma, Ype, Borst, J. Gerard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490249/
https://www.ncbi.nlm.nih.gov/pubmed/26190969
http://dx.doi.org/10.3389/fncel.2015.00234