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Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD

Posttraumatic stress disorder (PTSD), a trauma-related mental disorder, is associated with mitochondrial dysfunction in the brain. However, the biologic approach to identifying the mitochondria-focused genes underlying the pathogenesis of PTSD is still in its infancy. Previous research, using a huma...

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Detalles Bibliográficos
Autores principales: Zhang, L, Li, H, Hu, X, Benedek, D M, Fullerton, C S, Forsten, R D, Naifeh, J A, Li, X, Wu, H, Benevides, K N, Le, T, Smerin, S, Russell, D W, Ursano, R J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490278/
https://www.ncbi.nlm.nih.gov/pubmed/26080315
http://dx.doi.org/10.1038/tp.2015.65