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Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

There is great interest in blood-based markers of Alzheimer's disease (AD), especially in its pre-symptomatic stages. Therefore, we aimed to identify plasma proteins whose levels associate with potential markers of pre-symptomatic AD. We also aimed to characterise confounding by genetics and th...

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Detalles Bibliográficos
Autores principales: Kiddle, S J, Steves, C J, Mehta, M, Simmons, A, Xu, X, Newhouse, S, Sattlecker, M, Ashton, N J, Bazenet, C, Killick, R, Adnan, J, Westman, E, Nelson, S, Soininen, H, Kloszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Curtis, C, Breen, G, Williams, S C R, Lovestone, S, Spector, T D, Dobson, R J B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490288/
https://www.ncbi.nlm.nih.gov/pubmed/26080319
http://dx.doi.org/10.1038/tp.2015.78