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Revisiting the intraperoxisomal pathway of mammalian PEX7

Newly synthesized peroxisomal proteins containing a cleavable type 2 targeting signal (PTS2) are transported to the peroxisome by a cytosolic PEX5-PEX7 complex. There, the trimeric complex becomes inserted into the peroxisomal membrane docking/translocation machinery (DTM), a step that leads to the...

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Detalles Bibliográficos
Autores principales: Rodrigues, Tony A., Grou, Cláudia P., Azevedo, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490337/
https://www.ncbi.nlm.nih.gov/pubmed/26138649
http://dx.doi.org/10.1038/srep11806