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Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates
The development of an efficacious Plasmodium falciparum malaria vaccine remains a top priority for global health. Vaccination with irradiated sporozoites is able to provide complete sterile protection through the action of CD8(+) T cells at the liver-stage of infection. However, this method is curre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490344/ https://www.ncbi.nlm.nih.gov/pubmed/26139288 http://dx.doi.org/10.1038/srep11820 |