Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I

Type III R–M enzymes were identified >40 years ago and yet there is no structural information on these multisubunit enzymes. Here we report the structure of a Type III R–M system, consisting of the entire EcoP15I complex (Mod(2)Res(1)) bound to DNA. The structure suggests how ATP hydrolysis is co...

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Detalles Bibliográficos
Autores principales: Gupta, Yogesh K., Chan, Siu-Hong, Xu, Shuang-yong, Aggarwal, Aneel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490356/
https://www.ncbi.nlm.nih.gov/pubmed/26067164
http://dx.doi.org/10.1038/ncomms8363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490356/
https://www.ncbi.nlm.nih.gov/pubmed/26067164
http://dx.doi.org/10.1038/ncomms8363

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