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Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I
Type III R–M enzymes were identified >40 years ago and yet there is no structural information on these multisubunit enzymes. Here we report the structure of a Type III R–M system, consisting of the entire EcoP15I complex (Mod(2)Res(1)) bound to DNA. The structure suggests how ATP hydrolysis is co...
Autores principales: | Gupta, Yogesh K., Chan, Siu-Hong, Xu, Shuang-yong, Aggarwal, Aneel K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490356/ https://www.ncbi.nlm.nih.gov/pubmed/26067164 http://dx.doi.org/10.1038/ncomms8363 |
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