Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

Beyond its role in host defense, bacterial DNA methylation also plays important roles in the regulation of gene expression, virulence and antibiotic resistance. Bacterial cells in a clonal population can generate epigenetic heterogeneity to increase population-level phenotypic plasticity. Single mol...

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Detalles Bibliográficos
Autores principales: Beaulaurier, John, Zhang, Xue-Song, Zhu, Shijia, Sebra, Robert, Rosenbluh, Chaggai, Deikus, Gintaras, Shen, Nan, Munera, Diana, Waldor, Matthew K., Chess, Andrew, Blaser, Martin J., Schadt, Eric E., Fang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490391/
https://www.ncbi.nlm.nih.gov/pubmed/26074426
http://dx.doi.org/10.1038/ncomms8438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490391/
https://www.ncbi.nlm.nih.gov/pubmed/26074426
http://dx.doi.org/10.1038/ncomms8438

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