WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway

Stress exposure triggers ligand-independent EGF receptor (EGFR) endocytosis, but its post-endocytic fate and role in regulating signalling are unclear. We show that the p38 MAP kinase-dependent, EGFR tyrosine kinase (TK)-independent EGFR internalization induced by ultraviolet light C (UVC) or the ca...

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Detalles Bibliográficos
Autores principales: Tomas, Alejandra, Vaughan, Simon O., Burgoyne, Thomas, Sorkin, Alexander, Hartley, John A., Hochhauser, Daniel, Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490399/
https://www.ncbi.nlm.nih.gov/pubmed/26066081
http://dx.doi.org/10.1038/ncomms8324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490399/
https://www.ncbi.nlm.nih.gov/pubmed/26066081
http://dx.doi.org/10.1038/ncomms8324

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