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Dysregulation of PAK1 Is Associated with DNA Damage and Is of Prognostic Importance in Primary Esophageal Small Cell Carcinoma

Primary esophageal small cell carcinoma (PESCC) is a rare, but fatal subtype of esophageal carcinoma. No effective therapeutic regimen for it. P21-activated kinase 1 (PAK1) is known to function as an integrator and an indispensable node of major growth factor signaling and the molecular therapy targ...

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Detalles Bibliográficos
Autores principales: Gan, Jinfeng, Zhang, Yuling, Ke, Xiurong, Tan, Chong, Ren, Hongzheng, Dong, Hongmei, Jiang, Jiali, Chen, Shaobin, Zhuang, Yixuan, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490427/
https://www.ncbi.nlm.nih.gov/pubmed/26023713
http://dx.doi.org/10.3390/ijms160612035