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Acetic Acid-Catalyzed Formation of N-Phenylphthalimide from Phthalanilic Acid: A Computational Study of the Mechanism

In glacial acetic acid, phthalanilic acid and its monosubstituents are known to be converted to the corresponding phthalimides in relatively good yields. In this study, we computationally investigated the experimentally proposed two-step (addition-elimination or cyclization-dehydration) mechanism at...

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Detalles Bibliográficos
Autores principales: Takahashi, Ohgi, Kirikoshi, Ryota, Manabe, Noriyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490437/
https://www.ncbi.nlm.nih.gov/pubmed/26030675
http://dx.doi.org/10.3390/ijms160612174