Hyperactive RAS/PI3-K/MAPK Signaling Cascade in Migration and Adhesion of Nf1 Haploinsufficient Mesenchymal Stem/Progenitor Cells

Neurofibromatosis type 1 (NF1) is an autosomal dominant disease caused by mutations in the NF1 tumor suppressor gene, which affect approximately 1 out of 3000 individuals. Patients with NF1 suffer from a range of malignant and nonmalignant manifestations such as plexiform neurofibromas and skeletal...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, He, Yongzheng, Sharma, Richa, Xing, Wen, Estwick, Selina A., Wu, Xiaohua, Rhodes, Steven D., Xu, Mingjiang, Yang, Feng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490447/
https://www.ncbi.nlm.nih.gov/pubmed/26039236
http://dx.doi.org/10.3390/ijms160612345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490447/
https://www.ncbi.nlm.nih.gov/pubmed/26039236
http://dx.doi.org/10.3390/ijms160612345

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