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Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H(2)S Signaling via DNA Hypermethylation of CSE Promoter

Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases. Unfortunately, Hcy-lowering strategies were found to have limited effects in reducing cardiovascular events. The underlying mechanisms remain unclear. Increasing evidence reveals a role of...

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Detalles Bibliográficos
Autores principales: Li, Jiao-Jiao, Li, Qian, Du, Hua-Ping, Wang, Ya-Li, You, Shou-Jiang, Wang, Fen, Xu, Xing-Shun, Cheng, Jian, Cao, Yong-Jun, Liu, Chun-Feng, Hu, Li-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490461/
https://www.ncbi.nlm.nih.gov/pubmed/26047341
http://dx.doi.org/10.3390/ijms160612560