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Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H(2)S Signaling via DNA Hypermethylation of CSE Promoter
Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases. Unfortunately, Hcy-lowering strategies were found to have limited effects in reducing cardiovascular events. The underlying mechanisms remain unclear. Increasing evidence reveals a role of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490461/ https://www.ncbi.nlm.nih.gov/pubmed/26047341 http://dx.doi.org/10.3390/ijms160612560 |